---
title: clearance_astrazeneca
canonical_url: "https://www.modelscope.cn/datasets/jablonkagroup/clearance_astrazeneca"
md_url: "https://www.modelscope.cn/datasets/jablonkagroup/clearance_astrazeneca.md"
repository: jablonkagroup/clearance_astrazeneca
last_updated: 2025-05-28
license: "Apache License 2.0"
storage_size: "621 KB"
downloads: 655
stars: 0
---

# clearance_astrazeneca

> clearance_astrazeneca - jablonkagroup 在 ModelScope 开源的数据集。Drug clearance is defined as the volume of plasma cleared of a drug over a specified time period and it measures the rate at which the active drug is removed from the body. This is a dataset curated…

jablonkagroup/clearance_astrazeneca 是 ModelScope 魔搭社区上的数据集，存储大小 621 KB，采用 Apache License 2.0 许可。

- **Repository**: jablonkagroup/clearance_astrazeneca
- **License**: Apache License 2.0
- **Storage size**: 621 KB
- **Downloads**: 655
- **Stars**: 0
- **Last updated**: 2025-05-28

Source: https://www.modelscope.cn/datasets/jablonkagroup/clearance_astrazeneca

---

## Dataset Details

### Dataset Description

Drug clearance is defined as the volume of plasma cleared of a drug
over a specified time period and it measures the rate at which the active drug
is removed from the body. This is a dataset curated from ChEMBL database containing
experimental results on intrinsic clearance, deposited from AstraZeneca. It
contains clearance measures from two experiments types, hepatocyte and microsomes.

- **Curated by:**
- **License:** CC BY 4.0

### Dataset Sources

- [corresponding publication](http://dx.doi.org/10.6019/CHEMBL3301361)
- [corresponding publication](https://doi.org/10.1016/j.ejmech.2012.06.043)
- [data source](https://tdcommons.ai/single_pred_tasks/adme/#clearance-astrazeneca)

## Citation

<!-- If there is a paper or blog post introducing the dataset, the APA and Bibtex information for that should go in this section. -->

**BibTeX:**

```bibtex
@techreport{Hersey2015,
doi = {10.6019/chembl3301361},
url = {https://doi.org/10.6019/chembl3301361},
year = {2015},
month = feb,
publisher = {{EMBL}-{EBI}},
author = {Anne Hersey},
title = {{ChEMBL} Deposited Data Set - {AZ dataset}}
@article{Di2012,
doi = {10.1016/j.ejmech.2012.06.043},
url = {https://doi.org/10.1016/j.ejmech.2012.06.043},
year = {2012},
month = nov,
publisher = {Elsevier BV},
volume = {57},
pages = {441--448},
author = {Li Di and Christopher Keefer and Dennis O. Scott and Timothy J. Strelevitz
and George Chang and Yi-An Bi and Yurong Lai and Jonathon Duckworth and
Katherine Fenner and Matthew D. Troutman and R. Scott Obach},
title = {Mechanistic insights from comparing intrinsic clearance values between
human liver microsomes and hepatocytes to guide drug design},
journal = {European Journal of Medicinal Chemistry}
```