---
title: ames_mutagenicity
canonical_url: "https://www.modelscope.cn/datasets/jablonkagroup/ames_mutagenicity"
md_url: "https://www.modelscope.cn/datasets/jablonkagroup/ames_mutagenicity.md"
repository: jablonkagroup/ames_mutagenicity
last_updated: 2025-05-27
license: "Apache License 2.0"
storage_size: "11 MB"
downloads: 1062
stars: 0
---

# ames_mutagenicity

> ames_mutagenicity - jablonkagroup 在 ModelScope 开源的数据集。Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used…

jablonkagroup/ames_mutagenicity 是 ModelScope 魔搭社区上的数据集，存储大小 11 MB，采用 Apache License 2.0 许可。

- **Repository**: jablonkagroup/ames_mutagenicity
- **License**: Apache License 2.0
- **Storage size**: 11 MB
- **Downloads**: 1062
- **Stars**: 0
- **Last updated**: 2025-05-27

Source: https://www.modelscope.cn/datasets/jablonkagroup/ames_mutagenicity

---

## Dataset Details

### Dataset Description

Mutagenicity means the ability of a drug to induce genetic alterations.
Drugs that can cause damage to the DNA can result in cell death or other severe
adverse effects. Nowadays, the most widely used assay for testing the mutagenicity
of compounds is the Ames experiment which was invented by a professor named
Ames. The Ames test is a short term bacterial reverse mutation assay detecting
a large number of compounds which can induce genetic damage and frameshift mutations.
The dataset is aggregated from four papers.

- **Curated by:**
- **License:** CC BY 4.0

### Dataset Sources

- [corresponding publication](https://doi.org/10.1021/ci300400a)
- [Data source](https://tdcommons.ai/single_pred_tasks/tox/#ames-mutagenicity)

## Citation

<!-- If there is a paper or blog post introducing the dataset, the APA and Bibtex information for that should go in this section. -->

**BibTeX:**

```bibtex
@article{Xu2012,
doi = {10.1021/ci300400a},
url = {https://doi.org/10.1021/ci300400a},
year = {2012},
month = oct,
publisher = {American Chemical Society (ACS)},
volume = {52},
number = {11},
pages = {2840--2847},
author = {Congying Xu and Feixiong Cheng and Lei Chen and
Zheng Du and Weihua Li and Guixia Liu and Philip W. Lee and Yun Tang},
title = {In silico Prediction of Chemical Ames Mutagenicity},
journal = {Journal of Chemical Information and Modeling}
```